ABSTRACT
El eritema ab igne es una entidad que fue descrita por primera vez por Buschke como hitze melanosis (melanosis inducida por calor), en piernas de personas que trabajaban frente a fuegos abiertos o estufas de carbón. Se define como lesiones cutáneas eritematosas o hiperpigmentadas en un patrón reticulado característico, secundario a la exposición crónica de bajos niveles de radiación infrarroja. A pesar que la aparición de calefacción centralha significado una dramática disminución en su incidencia, aún se describen casos de causa cultural, médica o laboral. Una de susconsecuencias más graves es la posibilidad de aparición de un carcinoma espinocelular sobre la lesión. A continuación se presenta un caso clínico de etiología laboral y se realizará una revisión de la literatura.
Erythema ab igne is an entity that was first described by Buschke as hitze melanosis (heat-induced melanosis), in the legs of people working in front of open fires or coal stoves. It is defined as erythematous or hyperpigmented skin lesions in a reticulated pattern. The main cause is the chronic exposure tolow levels of infrared radiation. Although the occurrence of central heating has meant a dramatic decrease in incidence, cultural, medical or occupational causes are still described. One of the most serious consequences is the possibility of develoging an squamous cell carcinoma. We present a case of occupational aetiology and a review of the literature.
Subject(s)
Humans , Adult , Female , Hot Temperature/adverse effects , Erythema/diagnosis , Erythema/etiology , Occupational Diseases , Diagnosis, Differential , ThighABSTRACT
Objective. To define the presence of lung metastasis in bitches with malignant mammary neoplasms. Materials and methods. Thirty female dogs that were attended at Veterinary Hospital (University of Antioquia, Medellin, Colombia) were selected for the study. At consultation clinical variables and grade of mammary and inguinal lymph node compromise were registered. Latero-lateral and ventral-dorsal radiographic images of thorax were done for identification of radiographic lesions suggestive of lung metastasis. At surgery biopsies of affected mammary glands were taken for histopathological study and classification of tumors. Data were analyzed by descriptive statistics. Results. The average (± standard error) age at clinical diagnosis was 10.87±2.65 year old. French poodle (46.6%) cross-breed (13.3%) and Schnauzer (10%) were the breeds most frequently affected by mammary tumors. The most frequent tumor found was carcinoma (81%), followed by adenoma (8.1%), and other types (10.8%). The most frequently affected mammary glands by tumors were the right and the left inguinal glands (70% and 66.6%, respectively). Five out of 30 bitches (16.6%) had lung metastasis according to radiographic examination. From this group of dogs, 4 out of 5 neoplasms (80%) were diagnosed as complex carcinoma by histopathology diagnosis. Conclusions. We provide evidence suggesting that complex carcinoma is the most frequent mammary tumor in bitches in our city and it is highly related to lung metastasis.
Objetivo. Definir la presencia de metástasis pulmonar en perras con tumores mamarios. Materiales y métodos. En una muestra de 30 perras atendidas en el Hospital Veterinario de la Universidad de Antioquia (Medellín, Colombia) con diagnóstico de tumores mamarios, al momento de la consulta, fueron registrados las variables clínicas y el grado de compromiso de las glándulas mamarias y de los nódulos linfáticos. Imágenes radiográficas latero-laterales y ventro-dorsales del tórax fueron tomadas para la identificación de hallazgos radiográficos compatibles con metástasis pulmonar. Biopsias mamarias afectadas fueron sometidas a estudio histopatológico y clasificación del tipo de tumor. Los datos fueron analizados mediante estadística descriptiva. Resultados. La edad promedio (± error estándar) al diagnóstico clínico fue 10.87 ± 2.65 años de edad. La raza más frecuentemente afectada fue la French poodle (46.6%) seguida de perros cruzados (13.3%) y Schnauzer (10%). El carcinoma fue el tumor más hallado (81%) seguido del adenoma (8.1%) y otros tipos de tumor (10.8%). Las glándulas mamarias más afectadas fueron las inguinales derecha (70%) e izquierda (66.6%). Cinco de las 30 pacientes (16.6%), presentaron metástasis a pulmón. Entre estas, 4 de 5 (80%) tenían carcinoma complejo. Conclusiones. El carcinoma complejo fue la neoplasia más frecuente y es el tipo más relacionado con metástasis pulmonar.
Subject(s)
Dog Diseases , Lung , Neoplasm MetastasisABSTRACT
La Enteritis Eosinofílica Idiopática (EEI) es una enfermedad de causa desconocida, reportada en los humanos y en varias especies animales. En el bovino se ha aceptado desde 1998 como una entidad poco común, con escasos reportes a nivel mundial. En este estudio se documenta una vaca que presentó inflamación intestinal de curso crónico, diagnosticada como EEI con base en el análisis de los hallazgos clínicos, histopatológicos y la exclusión de otras enfermedades intestinales. Esta comunicación constituye el primer reporte en Colombia de esta condición en el bovino y tiene como objetivo describir los hallazgos clínicos y anatomopatológicos encontrados y discutir sus posibles causas y mecanismos de enfermedad. Debido a que no se identificaron agentes infecciosos en el caso estudiado y a que la vaca presentó concomitantemente neoplasias, se postula como mecanismo de enfermedad más probable, el síndrome hipereosinofilia paraneoplásica.
Idiopathic Eosinophilic enteritis (IEE) is a disease of unknown cause reported in humans and various animal species. In cattle it has been accepted since 1998 as a rare entity, with few reports worldwide. This study documents the process of a cow that showed intestinal inflammation of chronic characteristics, diagnosed with IEE based on clinical and histopathological analysis as well as the exclusion of other intestinal diseases. This account is based on the first report of this condition in Colombian cattle and aims to describe clinical and anatomopathologic findings and the discussion of its possible causes and mechanisms of the disease. Because no infectious agents were identified in the case studied, and the fact hat the cow presented related neoplasms, the most probable mechanism of disease presented is the, paraneoplastic hypereosinophilia syndrome.
Subject(s)
Cattle , Hypersensitivity , Intestines , PathologyABSTRACT
Existe una gran variedad de lesiones o condiciones que producen un cambio de coloración o discromía en la mucosa oral. Entre éstas se encuentran las pigmentaciones que pueden ser de origen exógeno o endógeno y lesiones tumorales. Los pigmentos endógenos incluyen la melanina, hemoglobina, hemosiderina y caroteno. En cambio, las pigmentaciones exógenas se pueden provocar por tatuajes, intoxicación por metales pesados y tinciones.
There are a variety of injuries or conditions that produce a color change or dyschromia in oral mucosa. These dyschromias include pigmentation, that may be of endogenous or exogenous origin and malignant tumor. Endogenous pigments include melanin, hemoglobin, hemosiderin, and carotene. Instead exogenous pigmentation can result from tattoos, heavy metals and stains.
Subject(s)
Humans , Melanoma , Mouth Neoplasms , Mouth Mucosa/pathology , Pigmentation Disorders , Diagnosis, DifferentialABSTRACT
Background: Orofacial clefts are common and have a great medical and social importance. The Latin American Study of Congenital Malformations (ECLAMC), has maintained an epidemiological surveillance of congenital malformations since 1969, allowing the evaluation of trends in the prevalence of malformations. Aim: To evaluate the evolution curve of prevalence rates of orofacial clefts from 1971 to 2008. Material and Methods: All cases of orofacial clefts, occurring in newborns from the maternity of a university hospital from January 2000 to December 2008, were recorded as part of the ECLAMC. Historical information about the rates of the malformation between 1971 and 1999, was obtained from previous manuscripts of the authors. Results: In the study period, 15,635 children were born and 46 had cleft lip-palate (3). This rate is significantly higher than those observed previously, that fuctuated between 1.5 and 1.7. The prevalence rates of cleft lip remained stable from 1971 to 1999 and suffered a brisk and significant rise in the period 2000-2008 When the period is analyzed year by year, the increase in rates is observed in the last two years. The rates of cleft palate suffered a slight non significant rise until 2000. Conclusions: The increased rates of cleft lip palate observed in the last two years of the observation period may be a random result and should be monitored in the future.